try using an amt dt2 or behringer gdi.
set to classic,high gain and california.
set the bass and treble below the 9 0clock point.
set the bass around 830 and treble almost zero.
gain depending on your preferrence.
for single coils,set the gain slightly above 9 0clock.
boost it with an od.
recommended od would be maxon od9,od808,voodoo labs sparkle drive.
any other ods would work fine.
the next thing u have to do is sit down,shape your amp eq thoroughly.
bring the mids lower on the amp.
the classic setting brings out the closest amp sound.
and it brings out natural mids too.
so you hafta lower down the mids on the amps.
try twiddling between california and brit.
and most importantly,shaping the amps eq.
from marshalls,to mesas,to krank,you can get the closest sound to it.
but the key to getting the tone is to sit down,tweak the eqs,so on and so forth.
it requires lots of patience and time.
and the end of the day,it'll be a joy rockin out with such tone!
trust me.
try it!
hope it works.