When I think of a Tele, I'm reminded of the roadhouse twang. The kind of twang that only a Tele can give you.
I mean, that's why people go for Teles in the first place, right? Aesthetics aside.
Following in that line of thought, there really is no point in getting a Tele if you plan to stick in humbuckers and all.
I personally would never emulate John 5 nor Jim Root.
A Tele with super-hot pups will give you an acceptable heavy sound.
But a Les Paul, fitted with low-output single coils, can never and will never give you that true Tele twang!