Peter Green's distinctive sound comes from having the pickup magnetically out-of-phase.
The Jimmy Page sounds I believe are only electronically out-of-phase.
They are not the same.
As to if it makes a difference, yes it does! The (electronically) out-of-phase sound is weaker and hollow.
I recently made this mod on my guitar, to get the 2 humbuckers out-of-phase with each other.
You will hear the difference when clean for sure!
Also, the Page wiring with the 21 sounds will let you put each pup out-of-phase with itself as well as the 2 pups out-of-phase with each other.