for a start, im playing in G# D# G# C# F# tuning. ( YES PERIPHERY!)
the 166 b string is superb, very good clarity and tension.
However you might have to file your nut slightly to fit in that fat string and make sure the B string is able to go through your bass's bridge loader. You also have to consider if the B string would be too near the fret ends, especially at the 1st ,2nd and 3rd frets.
oh yes one more thing, u might have to file your bridge saddle as well or change a new one to accommodate to the new positioning of the B string.