i use angled cables for my pedals and straight or angled depending on my guitar. if the jack is on the front face of the guitar like in a strat or angled upwards at the side of the body like some Ibanez guitars i use a straight. if the jack is at a right angle on the side of the body like a Les Paul i use an angled jack. and i always loop my cable through my strap cause i hate it cables coming out when i'm moving around.
i just started using a wireless that one of my buddies lent me to try out. so far it seems ok...not too much tone coloring and it's nice to not be tied down by your cable, it doesn't tangle with your legs. the downside is that the cable seems to keep coming out of the jack so it ends up hanging from the battery pack (which is currently taped to the strap, which in turn affects the balance of the guitar). i will need to fix this. also, as with most wireless systems, there's a bit of tone coloring. it's not obvious enough to bother me much though, and the audience probably can't tell anyway.
