depending on your usage , if playing live at a very noisy like those band who plays in shanghai dolly or broiler room or church, cant hear the difference actually. If recording or playing alone in your bedroom, you can hear the difference only if you A/B them one after another. Up to you to weigh the price against the slight difference in the tone.
I myself bought a Ibanez TS808HW because i can hear the difference for this handwired unit against the normal factory produced, although not a great deal of difference, to me its just an collector item to satisfy my gear hunger without practical justification.